Nucleosides and Analogues
Accela Chembio Inc Thymidine | 100g | 50-89-5 | MFCD00006537 | 98% | Shelf Life: 1800 Days | Light Sensitive/+4
Thymidine | 100g | 50-89-5 | MFCD00006537 | 98% | Shelf Life: 1800 Days | Light Sensitive/+4
Medchemexpress LLC Uridine 5'-monophosphate | 58-97-9 | MFCD00067346 | 99.8% | 324.18 g/mol | C9H13N2O9P | 50 MG
Uridine 5'-monophosphate (UMP) is a pyrimidine ribonucleotide used as a biochemical research reagent and metabolite reference. It is commonly used in enzymatic assays, nucleotide metabolism studies, and as a standard for analytical methods. The material is supplied in small pack sizes for laboratory use and is characterized for purity and identity.
- Suitable as a metabolite reference and biochemical reagent.
- High purity for reproducible analytical and enzymatic assays.
- Provided in small pack sizes for research-scale experiments.
- Water-soluble for straightforward aqueous formulations.
- Characterized with molecular formula and molecular weight for identification.
![eMolecules Medchem Express / NADP (sodium salt) / 100mg / 446274366 / HY-F0002 / / 1184-16-3 / [null] / 765.390 / C21H27N7NaO17P3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502446349.PNG-250.jpg)
eMolecules Medchem Express / NADP (sodium salt) / 100mg / 446274366 / HY-F0002 / / 1184-16-3 / [null] / 765.390 / C21H27N7NaO17P3
Medchem Express / NADP (sodium salt) / 100mg / 446274366 / HY-F0002 / / 1184-16-3 / [null] / 765.390 / C21H27N7NaO17P3
Apexbio Technology LLC LDE225 Diphosphate 1218778-77-8 5mg
LDE225 Diphosphate (CAS 1218778-77-8) is a highly potent and selective antagonist of the Smoothened (Smo) receptor a seven-transmembrane protein involved in the Hedgehog (Hh) signaling pathway LDE225 inhibits Smo with IC50 values of 1 3 nM for murine and 2 5 nM for human Smo resulting in suppression of Hh signaling This pathway is implicated in cellular differentiation proliferation and oncogenesis In vitro LDE225 selectively binds Smo inhibiting Hh-dependent tumor cell growth In vivo it demonstrates dose-dependent antitumor efficacy in medulloblastoma xenograft mouse models LDE225 continues to be explored as a research tool and therapeutic candidate in Hh pathway-driven malignancies
Cayman Chemical 5-chloro-5-DeoxyadenosIn 1g
A nucleoside analog used as a substrate in the biosynthesis of the anticancer agent salinosporamide A
Apexbio Technology LLC 2'-O-Methyl-N6-Methyl-ATP 50ul (100 mM)
2p-O-Methyl-N6-Methyl-ATP is a chemically modified ATP analog bearing methyl substitutions at the N6 position of adenine and the 2 -hydroxyl group of the ribose sugar 2p-O-Methyl-N6-Methyl-ATP is designed to facilitate the study of RNA methylation processes and RNA protein interactions supporting the mechanistic exploration of RNA-modifying enzymes and epigenetic regulatory pathways Based on these properties 2p-O-Methyl-N6-Methyl-ATP holds research potential in investigations of ligand RNA interactions and drug discovery applications targeting RNA-related biological processes
Apexbio Technology LLC 2'-O-Methyl-2-Amino-ATP 100ul (100 mM)
2p-O-Methyl-2-Amino-ATP is a modified nucleoside triphosphate incorporating methylation at the ribose 2 -hydroxyl group and an amino substitution at the 2 position of the adenine base It is designed to alter nucleotide biochemical properties impacting RNA stability and structure upon enzymatic incorporation In in vitro transcription assays 2p-O-Methyl-2-Amino-ATP demonstrates an ability to increase RNA resistance to exonuclease-mediated degradation and induce altered RNA secondary structures Based on these properties 2p-O-Methyl-2-Amino-ATP holds research potential in studies of RNA folding dynamics stability assays RNA-protein interactions and analyses involving chemically modified RNA in biomedical research
Apexbio Technology LLC LDE225 Diphosphate 1218778-77-8 10mM (in 1mL DMSO)
LDE225 Diphosphate (CAS 1218778-77-8) is a highly potent and selective antagonist of the Smoothened (Smo) receptor a seven-transmembrane protein involved in the Hedgehog (Hh) signaling pathway LDE225 inhibits Smo with IC50 values of 1 3 nM for murine and 2 5 nM for human Smo resulting in suppression of Hh signaling This pathway is implicated in cellular differentiation proliferation and oncogenesis In vitro LDE225 selectively binds Smo inhibiting Hh-dependent tumor cell growth In vivo it demonstrates dose-dependent antitumor efficacy in medulloblastoma xenograft mouse models LDE225 continues to be explored as a research tool and therapeutic candidate in Hh pathway-driven malignancies